LDL Cholesterol, Direct
0020257
 
Ordering Recommendation
Mnemonic
LDL D
Methodology
Quantitative Detergent Solubilization/ Enzymatic
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Plasma separator tube or serum separator tube. Also acceptable: Green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA).  
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
 
Remarks
 
Stability
After separation from cells: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 1 month  
Reference Interval


Age Desirable Borderline Higher Risk
0-​19 years 109 mg/dL or less 110-​129 mg/dL 130 mg/dL or greater
20 years and older 129 mg/dL or less (99 mg/dL or less if patient has CHD) 130-​159 mg/dL 160 mg/dL or greater
Interpretive Data
CHD Risk Factors:
+1 Age: Men, 45 years and older
Women, 55 years and older or premature menopause without estrogen therapy
+1 Family history of premature CHD
+1 Current smoking
+1 Hypertension
+1 Diabetes mellitus
+1 Low HDL Cholesterol: 39 mg/dL or less
-1 High HDL Cholesterol: 60 mg/dL or greater

LDL Cholesterol: Therapeutic goal
99 mg/dL or less if CHD is present (Optional 69 mg/dL or less).
129 mg/dL or less if no CHD and two or more risk factors.
159 mg/dL or less if no CHD.
(Circulation 2004; 110:227-39)
Note
CPT Code(s)
83721
Components
Component Test Code*Component Chart Name
0020257LDL Cholesterol, Direct
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • Direct LDL
  • LDL
  • Low Density Lipoprotein