Ordering Recommendation

Determine exposure to HBV infection. May be helpful in determining which patients are at risk for HBV reactivation and would benefit from prophylactic nucleoside analog treatment prior to initiation of immunosuppression therapy.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport tube. (Min: 0.5 mL) Also acceptable: K2EDTA plasma.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Heparinized plasma. Specimens containing particulate material. Heat-inactivated, severely hemolyzed, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: Indefinitely (avoid repeated freeze/thaw cycles)

Methodology

Qualitative Chemiluminescent Immunoassay (CLIA)

Performed

Sun-Sat

Reported

Within 24 hours

Reference Interval

Test Number
Components
Reference Interval
  Hepatitis B Core Antibodies, Total Negative

Interpretive Data

This assay should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cell, Tissues and Cellular and Tissue-Based Products (HCT/P).

Compliance Category

FDA

Note

This assay tests for IgG and IgM antibodies, but does not differentiate between them.

Hotline History

N/A

CPT Codes

86704

Components

Component Test Code* Component Chart Name LOINC
0020091 Hepatitis B Core Antibodies, Total 13952-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Anti Core Antibodies
  • Anti-Hepatitis Bc
  • Antibody to Hepatitis Bc
  • Core Antibody IgG/IgM
  • HBV Core Total
  • Hep B Core Ab IgG/IgM, Hep Bc Ab IgG/IgM
  • Hep B Core Total Ab
  • Hepatitis B Immune Status Profile, Serum
Hepatitis B Virus Core Antibodies (Total)