Maternal T Cell Engraftment in SCID, Maternal Specimen
2014704
Ordering Recommendation

Monitor engraftment of maternal T cells in patients with severe combined immunodeficiency (SCID) prior to allogenic stem cell transplantation.

Mnemonic
SCID-MAT
Methodology
Polymerase Chain Reaction/Fragment Analysis
Performed
Sun-Sat
Reported
5-9 days
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA), Pink (K2EDTA), or Yellow (ACD Solution A).
New York State Clients: Lavender (EDTA). Collect Monday-Thursday only. 
Specimen Preparation
Transport 3 mL whole blood. (Min: 1 mL)
New York State Clients: Transport 14 mL whole blood. (Min: 6 mL). Do not send to ARUP Laboratories. Specimens must be received at performing laboratory within 24 hours of collection. For specimen requirements and direct submission instructions please contact ARUP Referral Testing at (800) 242-2787, ext. 5145. 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
 
Remarks
 
Stability
Ambient: 1 week; Refrigerated: 1 month; Frozen: 6 months
New York State Clients: Ambient: 24 hours; Refrigerated: Unacceptable; Frozen: Unacceptable 
Reference Interval
By report
Interpretive Data
Refer to report.

Note
To complete Maternal T Cell Engraftment in SCID testing, samples should be collected to perform the following three tests: (1) A buccal swab or brush collected from the patient for Maternal T Cell Engraftment in SCID, Pre-Engraftment Specimen (ARUP test code 2014694), used as a genetic baseline for the patient. (2) A peripheral blood sample from the biological mother for Maternal T Cell Engraftment in SCID, Maternal Specimen (ARUP test code 2014704), used as a genetic baseline for the mother. (3) A peripheral blood sample collected from the patient for Maternal T Cell Engraftment in SCID, (ARUP test code 2014699). T cells isolated from the blood sample will be genotyped for comparison to the patient and biological mother baseline genotypes. If T cell sorting is not completed on the blood sample before submission, BMT Cell Isolation (ARUP test code 2005498) will be added. Additional charges apply.
Hotline History
View Hotline History
CPT Code(s)
See CPT code for Maternal T Cell Engraftment in SCID, Pre-Engraftment Specimen (ARUP test code 2014694)
Components
Component Test Code*Component Chart NameLOINC
2014705Maternal Specimen, Maternal Engraftment
2014706Maternal Engraftment, Informative Loci
2014707Maternal Engraftment, Mat Spec Interp
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please view this test within the Laboratory Test Directory found at www.aruplab.com
Aliases
  • Maternal cell engraftment
  • Maternal engraftment
  • SCID
  • SCID engraftment