Polymyositis and Dermatomyositis Panel (INACTIVE as of 08/19/19: Refer to 3001783 in the August Hotline)
Ordering Recommendation
Qualitative Immunoprecipitation/Semi-Quantitative Multiplex Bead Assay/Qualitative Immunoblot
Mon, Tue, Thu, Fri
7-18 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum Separator Tube (SST). 
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transfer two 1 mL serum aliquots to ARUP Standard Transport Tubes. (Min: 0.5 mL/aliquot) 
Storage/Transport Temperature
Unacceptable Conditions
Hemolyzed, hyperlipemic, icteric, heat-treated or contaminated specimens. 
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year 
Reference Interval
Test Number
Reference Interval
0099592Jo-1 Antibody, IgG
29 AU/mL or lessNegative
30-40 AU/mLEquivocal
41 AU/mL or greaterPositive

 PL-7 (threonyl-tRNA synthetase) AntibodyNegative
 PL-12 (alanyl-tRNA synthetase) AntibodyNegative
 EJ (glycyl-tRNA synthetase) AntibodyNegative
 SRP (Signal Recognition Particle) AbNegative
 OJ (isoleucyl-tRNA synthetase) AntibodyNegative
 Mi-2 (nuclear helicase protein) AntibodyNegative
 P155/140 AntibodyNegative
 SAE1 (SUMO activating enzyme) AntibodyNegative
 MDA5 (CADM-140) AntibodyNegative
 NXP-2 (Nuclear matrix protein-2) AbNegative
 TIF-1 gamma (155 kDa) AntibodyNegative

Interpretive Data
Refer to report.

Statement D: Compliance Statement D: For laboratory tests using a manufactured RUO kit. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Antibodies:  PL-7, PL12, EJ, OJ, SRP, Jo-1, Mi-2, P155/140, SAE1, MDA5, NXP2, TIF1-gamma
Hotline History
View Hotline History
Component Test Code*Component Chart NameLOINC
0099592Jo-1 (Histidyl-tRNA Synthetase) Ab, IgG33571-1
2010852Mi-2 (nuclear helicase protein) Antibody18485-3
2010853PL-7 (threonyl-tRNA synthetase) Antibody33772-5
2010854PL-12 (alanyl-tRNA synthetase) Antibody33771-7
2010855P155/140 Antibody
2010856EJ (glycyl-tRNA synthetase) Antibody45149-2
2010859SRP (Signal Recognition Particle) Ab33921-8
2010860OJ (isoleucyl-tRNA synthetase) Antibody45152-6
2013962SAE1 (SUMO activating enzyme) Antibody82440-9
2013963NXP-2 (Nuclear matrix protein-2) Ab82426-8
2013964MDA5 (CADM-140) Antibody82424-3
2013965TIF-1 gamma (155 kDa) Antibody82448-2
2013997Myositis Interpretive Information48767-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please view this test within the Laboratory Test Directory found at www.aruplab.com