Use to diagnose H. pylori infection in adults (>17 years of age). For children and adolescents, refer to Helicobacter pylori Breath Test, Pediatric (2010925).
- Patient Preparation
- This test requires the adult patient (>17 years of age) to fast for 1 hour prior to test administration. The patient should not have taken antibiotics, proton pump inhibitors (e.g., Prilosec, Prevacid, Aciphex, Nexium), or bismuth preparations (e.g., Pepto-Bismol) within the previous 14 days. When used to monitor treatment, the test should be performed four weeks after cessation of definitive therapy. The patient should be informed that the Pranactin-Citric drink that will be administered contains phenylalanine. Phenylketonurics restrict dietary phenylalanine.
- BreathTek UBT Kit (ARUP Supply #51124 ) available online through eSupply using ARUP Connect™ or contact ARUPClient Services at (800) 522-2787.
- Specimen Preparation
- 1) Label breath collection bags with patient name, MRN, date and time of collection, and indicate Pre (blue) or Post (pink).
2) Collect the baseline (Pre) breath specimen according to the instructions in the BreathTek UBT kit.
3) After the allotted time, collect the Post breath specimen according to the instructions in the kit.
- Storage/Transport Temperature
- CRITICAL ROOM TEMPERATURE. Do not freeze.
- Unacceptable Conditions
- Underinflated bags. Pediatric specimens
- For a valid result, the post breath specimen must be collected between 15 and 30 minutes after the patient drinks the Pranactin-Citric solution.
- Ambient: 1 week; Refrigerated: Unacceptable; Frozen: Unacceptable
1. Use of antibiotics, proton pump inhibitors, and bismuth preparations during the preceding 2 weeks.
2. Administration of the breath test less than 4 weeks after completion of definitive therapy to eradicate H. pylori.
3. Premature or late collection of the post-dose specimen.
Known causes of false positive results include:
1. Patients with achlorhydria.
2. Rinsing the testing solution in the mouth or not using the straw provided in the kit, which can allow contact with urease-positive bacteria.
3. The presence of other gastric spiral organisms such as Helicobacter heilmanii.
|Component Test Code*||Component Chart Name||LOINC|
|0020646||H. pylori Breath Test||29891-9|
- 13C Urea Breath Test
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