Corticosterone Quantitative by HPLC-MS/MS, Serum or Plasma
Ordering Recommendation
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Mon, Wed, Fri
2-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
A morning specimen is preferred. 
Serum separator tube. Also acceptable: Plain red, pink (K2EDTA), plasma separator tube, green (sodium heparin), or green (lithium heparin). 
Specimen Preparation
Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL) 
Storage/Transport Temperature
Refrigerated. Also acceptable: Frozen. 
Unacceptable Conditions
Grossly hemolyzed specimens. 
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months. 
Reference Interval
Gestation Time, AgeReference Interval
Premature (26-28 weeks)235 - 1108 ng/dL
Premature (29-30 weeks)Not Established
Premature (31-35 weeks)150 - 1700 ng/dL
Full Term Newborn, 1-7 days70 - 850 ng/dL
8-29 daysNot Established
30 days-11 months80 - 1500 ng/dL

Age, Draw TimeReference Interval
1-16 years, morning135 - 1860 ng/dL
1-16 years, evening70 - 620 ng/dL
17 years and older, morning130 - 820 ng/dL
17 years and older, evening60 - 220 ng/dL

Interpretive Data

Statement B: Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Hotline History
Component Test Code*Component Chart NameLOINC
2008457Corticosterone, HPLC-MS/MS2139-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please view this test within the Laboratory Test Directory found at