Phosphatidylserine Antibodies, IgG and IgM
Ordering Recommendation

Preferred second-line test when seronegative antiphospholipid syndrome is strongly suspected. Order incrementally or concurrently with other noncriteria antiphospholipid antibody tests.

Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Sun, Tue, Wed, Fri, Sat
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum separator tube 
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Heat-inactivated, contaminated, grossly icteric, grossly hemolyzed, or severely lipemic specimens 
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
Test Number
Reference Interval
 Phosphatidylserine Antibody IgGLess than 11 U/mL
 Phosphatidylserine Antibody IgMLess than  25 U/mL

Interpretive Data
IgG and/or IgM antibodies to phosphatidylserine (aPS) may be associated with a positive test for anti-cardiolipin autoantibodies (aCL) and risk for obstetric antiphospholipid syndrome (APS). Strong clinical correlation is recommended in the absence of lupus anticoagulant, IgG and/or IgM cardiolipin and/or beta2 glycoprotein antibodies.

Isolated presence of IgM or IgG antibodies to aPS may have questionable clinical significance for APS and/or SLE.

If results are positive, repeat testing with two or more specimens drawn at least 12 weeks apart to demonstrate persistence of antibodies.

Results should not be used alone for diagnosis and must be interpreted in light of APS-specific clinical manifestations and/or other criteria phospholipid antibody tests.

Hotline History
View Hotline History
Component Test Code*Component Chart NameLOINC
0050906Phosphatidylserine Antibody IgG32032-5
0050907Phosphatidylserine Antibody IgM32033-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please view this test within the Laboratory Test Directory found at
  • Anti-Phosphatidylserine
  • Anti-Phosphatidylserine (aPS)
  • Antiphosphatidylserine
  • aPS Antibodies IgG, IgM, IgA