Useful as a biomarker of acute thallium exposure. For the assessment of chronic exposure, consider Thallium, Urine (0025019).
- Patient Preparation
- Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician).
- Royal Blue (K2EDTA or Na2EDTA).
- Specimen Preparation
- Transport 7 mL whole blood in the original collection tube. (Min: 0.5 mL)
- Storage/Transport Temperature
- Room temperature. Also acceptable: Refrigerated.
- Unacceptable Conditions
- Specimens collected in tubes other than Royal Blue (EDTA). Specimens transported in containers other than a Royal Blue (EDTA) tube or Trace Element-Free Transport Tube. Heparin anticoagulant. Clotted specimens.
- Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Blood thallium levels reflect recent exposure as thallium has a biological half-life of approximately 2 to 4 days. Blood levels greater than 100 µg/L are considered toxic and greater than 300 µg/L indicate severe ingestion. After severe thallium poisonings, reported symptoms have varying times of onset and include gastroenteritis, multi-organ failure and neurologic injury. Peripheral neuropathy and alopecia are well-documented effects of acute and chronic exposure. Human health effects from low-level thallium exposure are unknown.
|Component Test Code*||Component Chart Name||LOINC|
- WB thallium