Fetal Fibronectin
Ordering Recommendation

Assess risk of preterm delivery in less than or equal to 7-14 days from time of sample collection at 24 weeks 0 days to 34 weeks 6 days gestation when there are signs and symptoms of early preterm labor.

Semi-Quantitative Immunoassay/Immunosorbent
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Specimens for fetal fibronectin testing should be collected prior to collection of culture specimens.  Specimens should be obtained prior to digital cervical examination or vaginal probe, ultrasound examination as manipulation of the cervix may cause the release of fetal fibronectin. 

Testing should not be performed if the patient has had sexual intercourse within 24 hours prior to the sampling time because semen present may increase the possibility of a false positive result. 
Swab from the posterior fornix of the vagina or the ectocervical region of the external cervical os. Do not to contaminate the swab or cervicovaginal secretions with lubricants, soaps disinfectants or creams. 
Specimen Preparation
Specimens that are not tested within eight hours of collection must be stored, refrigerated, and tested within 72 hours of collection. Avoid extreme temperatures. Transport swab in Fetal Fibronectin Specimen Collection Kit (ARUP supply #32748). Available online through eSupply using ARUP Connect (TM) or contact Client Services at (800) 522-2787.  Required Information: Specimen must be labeled with gestational age and list patient condition as either "symptomatic" or "asymptomatic." 
Storage/Transport Temperature
Unacceptable Conditions
Specimens collected in or by any specimen device other than Fetal Fibronectin Specimen Collection Kit. 
Specimen source required. 
Ambient: 8 hours; Refrigerated: 3 days; Frozen: 2 weeks  Only one freeze/thaw cycle acceptable. 
Reference Interval
Normal: Interpretation by report.
Interpretive Data
Positive result when concentration is greater than or equal to 0.05 µg/mL

Hotline History
Component Test Code*Component Chart NameLOINC
0081024Gestation Age in Wks and Days49051-6
0081025Labor Symptoms57069-7
0082026fFN Labor Symptoms57069-7
0082027fFN Gestational Age
0082028fFN Interpretation48039-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please view this test within the Laboratory Test Directory found at www.aruplab.com
  • FFN