Not recommended for evaluation of pheochromocytoma or paraganglioma. Use to evaluate clinical symptoms of excess catecholamine secretion. For the assessment of pheochromocytoma and paraganglioma, refer to Metanephrines, Plasma (Free) (0050184) or Metanephrines Fractionated by HPLC-MS/MS, Urine (2007996).
- Patient Preparation
- Patient should be calm and supine for 30 minutes prior to collection.
- Green (sodium or lithium heparin). Collect on ice.
- Specimen Preparation
- Specimen should be centrifuged and frozen within one hour (refrigerated centrifuge is preferred but not required). Transfer 4 mL plasma to an ARUP Standard Transport Tube. (Min: 2.1 mL)
- Storage/Transport Temperature
- CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
- Unacceptable Conditions
- EDTA plasma, serum, or urine.
- After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozenat -20°C: 1 month; Frozen at -70°C: 1 year
|Test Number||Components||Reference Interval|
probability of a neuroendocrine tumor. Measurement of plasma or urine fractionated metanephrines provides better diagnostic sensitivity than measurement of catecholamines.
Higher catecholamine concentrations are observed in specimens collected from upright or standing adults. Epinephrine may be increased by approximately 20 percent and norepinephrine increased up to 700 pg/mL.
For optimum results, patient should be supine for 30 minutes prior to collection.
Children, particularly those under 2 years of age, often show an elevated catecholamine response to stress.
|Component Test Code*||Component Chart Name||LOINC|