Soluble Transferrin Receptor
Ordering Recommendation
Quantitative Immunoturbidimetry
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum separator tube or plasma separator tube. Also acceptable: green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA). 
Specimen Preparation
Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Contaminated, severely hemolyzed, icteric, or lipemic specimens. 
After separation from cells: Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month (avoid repeated freeze/thaw cycles) 
Reference Interval
Male - 18 years & older: 2.2-5.0 mg/L
Female - 18 years & older: 1.9-4.4 mg/L
Interpretive Data
People of African descent and those residing at 5,200 feet (1,600 meters) above sea level were found to have a 6% higher normal value. These differences were additive. Reference intervals have not been established for pregnant females, patients under 18 years of age, and recent or frequent blood donors.

Serum soluble transferrin receptor increases in iron deficiency and is usually unaffected by chronic disease states. In general, to increase sensitivity and specificity, the measurement of serum soluble transferrin receptor should be performed in combination with other tests of iron status, including ferritin, TIBC, and serum iron (refer to table below).

Tests for Changes in:
Iron Deficiency Anemia
Anemia of Chronic Disease
Iron Deficiency & Anemia of Chronic Disease
FerritinIron StoresLowHighNormal or High
TIBCIron StatusHighLowNormal or High
Serum IronIron StatusLowLowLow
sTfRIron StatusHighNormalHigh

Hotline History
Component Test Code*Component Chart NameLOINC
0070283Soluble Transferrin Receptor30248-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please view this test within the Laboratory Test Directory found at
  • sTfR
  • TfR
  • Transferrin Receptor
  • Transferrin Receptor Level