Coxsackie B Virus Antibodies
Ordering Recommendation

Detect neutralizing antibodies to coxsackie B virus.

Semi-Quantitative Serum Neutralization
Mon- Fri
6-9 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum separator tube or plain red. OR CSF. 
Specimen Preparation
Separate serum from cells within 2 hours of collection. Transfer 1 mL serum or CSF to an ARUP Standard Transport Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Mark specimens plainly as "acute" or "convalescent." 
Storage/Transport Temperature
Unacceptable Conditions
Contaminated, hemolyzed, or severely lipemic specimens. 
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
Coxsackie B1: Less than 1:10
Coxsackie B2: Less than 1:10
Coxsackie B3: Less than 1:10
Coxsackie B4: Less than 1:10
Coxsackie B5: Less than 1:10
Coxsackie B6: Less than 1:10
Interpretive Data
Single positive antibody titers of greater than or equal to 1:80 may indicate past or current infection. Seroconversion or an increase in titers between acute and convalescent sera of at least fourfold is considered strong evidence of current or recent infection.

The clinical significance and criteria for interpretation of results from CSF have not been established.
Hotline History
Component Test Code*Component Chart NameLOINC
0065111Coxsackie B Virus Antibody Type 15103-7
0065112Coxsackie B Virus Antibody Type 25105-2
0065113Coxsackie B Virus Antibody Type 35107-8
0065123Coxsackie B Virus Antibody Type 55111-0
0065124Coxsackie B Virus Antibody Type 65113-6
0065130Coxsackie B Virus Antibody Type 45109-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please view this test within the Laboratory Test Directory found at
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