Rheumatoid Factors, IgA, IgG, and IgM by ELISA
0051298
Ordering Recommendation
May aid in prognostication for rheumatoid arthritis. Rheumatoid Arthritis Panel (2003277) is preferred for the workup of suspected rheumatoid arthritis or undifferentiated inflammatory arthritides.
Mnemonic
RF PAN
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Mon, Wed, Fri
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
- Patient Preparation
- Collect
- Serum separator tube.
- Specimen Preparation
- Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)
- Storage/Transport Temperature
- Refrigerated.
- Unacceptable Conditions
- Contaminated, hemolyzed, icteric, or lipemic specimens.
- Remarks
- Stability
- After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
| Test Number | Components | Reference Interval |
|---|---|---|
| Rheumatoid Factor, IgG by ELISA | 6 Units or less | |
| Rheumatoid Factor, IgM by ELISA | 6 Units or less | |
| Rheumatoid Factor, IgA by ELISA | 6 Units or less |
Interpretive Data
The presence of all three rheumatoid factor (RF) isotypes at abnormal levels has high specificity for a diagnosis of rheumatoid arthritis (RA). However, the presence of RF isotypes in any combination may be found in a variety of conditions, including Sjogren syndrome and hepatitis infections.
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0051299 | Rheumatoid Factor, IgG by ELISA | 33314-6 |
| 0051300 | Rheumatoid Factor, IgM by ELISA | 11573-3 |
| 0051301 | Rheumatoid Factor, IgA by ELISA | 33313-8 |
Aliases
- RF Abs
- RF IgA IgG IgM
- RF Isotypes
- RF3