Legionella pneumophila Antibody (Types 1-6), IgM by IFA
Ordering Recommendation

May be useful when acute legionellosis is suspected; however, Legionella pneumophila Antigen, Urine (0070322) is preferred.

Semi-Quantitative Indirect Fluorescent Antibody
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum separator tube. 
Specimen Preparation
Separate serum from cell ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as acute or convalescent. 
Storage/Transport Temperature
Unacceptable Conditions
Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens. 
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
< 1:16
Interpretive Data
IgM antibody to Legionella pneumophila serotypes 1-6 is measured using an IgM-specific conjugate. It is recommended that the IgM test always be performed in conjunction with IgG antibody test.

The IgM response to Legionella tends to develop concurrently with the IgG response and may remain elevated as long as the IgG response remains elevated. Cross-reactions have been described with several species of bacteria and Mycoplasma.

Hotline History
View Hotline History
Component Test Code*Component Chart NameLOINC
0050274Legionella Pneumophila 1-6,IgM16133-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please view this test within the Laboratory Test Directory found at www.aruplab.com
  • L pneumophila IgM
  • L pneumophila Types 1-6 Ab
  • Legionella pneumophila IgM antibody
  • Legionnaires Disease Testing