LDL Subclasses
Ordering Recommendation

Differentiate LDL particles with respect to size to identify individuals with phenotype A (large LDL particles) or B (small LDL particles); considered as a nontraditional CVD risk marker.

Quantitative Electrophoresis
1-8 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Patient should be fasting for 12 hours prior to collection. 
Lavender (EDTA), Pink (K2EDTA), Plain Red, or Serum Separator Tube (SST). 
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.2 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Heparinized plasma. Specimens from patients receiving heparin. Grossly hemolyzed specimens. 
Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: Unacceptable 
Reference Interval
Test Number
Reference Interval
 Cholesterol, TotalAdults: 199 mg/dL or less
Children: 169 mg/dL or less
 LDL1 (LDL 1 Fraction)57 mg/dL or less
 LDL2 (LDL 2 Fraction)30 mg/dL or less
 LDL3 (LDL 3 Fraction)6 mg/dL or less
 LDL4 (LDL 4 Fraction)None Detected
 LDL5 (LDL 5 Fraction)None Detected
 LDL6 (LDL 6 Fraction)None Detected
 LDL7 (LDL 7 Fraction)None Detected
 Midband A25 mg/dL or less
 Midband B15 mg/dL or less
 Midband C23 mg/dL or less
 VLDL, Cholesterol22 mg/dL or less
 HDL-Cholesterol40-59 mg/dL
 Total LDL-Cholesterol130 mg/dL or less
 LDL PhenotypeBy report

Interpretive Data
LDL Type A: Indicative of Type A. Type A is characterized by mainly large buoyant LDL.
LDL Not Type A: Not indicative of Type A. Not type A is characterized by mainly small dense LDL. Small dense LDL is associated with an increased risk of coronary artery disease.

Hotline History
View Hotline History
Component Test Code*Component Chart NameLOINC
0050023LDL Phenotype35505-7
0050159Cholesterol, Total2093-3
0080531LDL1 (LDL 1 Fraction)91105-7
0080532LDL2 (LDL 2 Fraction)91106-5
0080533LDL3 (LDL 3 Fraction)91107-3
0080534LDL4 (LDL 4 Fraction)91108-1
0080535LDL5 (LDL 5 Fraction)91109-9
0080536LDL6 (LDL 6 Fraction)91110-7
0080537LDL7 (LDL 7 Fraction)91111-5
0081007VLDL, Cholesterol2091-7
0081008Midband C51002-4
0081009Midband B51003-2
0081010Midband A51004-0
0081011Total LDL-Cholesterol2089-1
2004029EER LDL Subclasses11526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please view this test within the Laboratory Test Directory found at www.aruplab.com
  • LDL fractions
  • LDL phenotype
  • LDL Subfractions
  • LDL Subtype
  • Low Density Lipoprotein Subclass Pattern