Ordering Recommendation

Allergen testing for patients in the south Atlantic region (Georgia, South Carolina, northern Florida).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Multiple patient encounters should be avoided.

Collect

Serum Separator Tube (SST). Multiple specimen tubes should be avoided.

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 4 mL serum to an ARUP Standard Transport Tube. (Min: 1.3 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Methodology

Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Performed

Sun-Sat

Reported

1-3 days

Reference Interval

Test Number
Components
Reference Interval
  Immunoglobulin E
Age Reference Interval (kU/L)
0-5 months 13 or less
6-12 months 34 or less
1-2 years 97 or less
3 years 199 or less
4-6 years 307 or less
7-8 years 403 or less
9-12 years 696 or less
13-15 years 629 or less
16-17 years 537 or less
18 years and older 214 or less

  Allergen, Fungi/Mold, A. alternata IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Box Elder/Maple Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Animal, Cat Dander IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Mountain Cedar Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Pigweed IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, Timothy Grass IgE Less than or equal to 0.34 kU/L
  Allergen, Fungi/Mold, Hormodendrum IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Elm Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Oak Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Birch Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Fungi/Mold, A. fumigatus IgE Less than or equal to 0.34 kU/L
  Allergen, Mites, D. pteronyssinus IgE Less than or equal to 0.34 kU/L
  Allergen, Mites, D. farinae IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, Bermuda Grass IgE Less than or equal to 0.34 kU/L
  Allergen, Fungi/Mold, P. notatum IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Common/Short Ragweed IgE Less than or equal to 0.34 kU/L
  Allergen, Insect, Cockroach, German IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Pecan Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, Bahia IgE Less than or equal to 0.34 kU/L
  Allergen, Animal, Mouse Epithelium IgE Less than or equal to 0.34 kU/L
  Allergen, Fungi/Mold, M. racemosus IgE Less than or equal to 0.34 kU/L
  Allergen, Animal, Dog Dander IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Nettle IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Sheep Sorrel IgE Less than or equal to 0.34 kU/L

Interpretive Data

Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivo reactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis.


Reporting Range (reported in kU/L) Probability of IgE Mediated Clinical Reaction Class Scoring
Less than 0.10 No significant level detected 0
0.10 - 0.34 Clinical relevance undetermined 0/1
0.35 - 0.70 Low 1
0.71 - 3.50 Moderate 2
3.51 - 17.50 High 3
17.51 - 50.00 Very high 4
50.01 - 100.00 Very high 5
Greater than 100.00 Very high 6

Compliance Category

FDA

Note

Allergens included in this panel: Alternaria alternata (tenuis), Aspergillus fumigatus, Bahia Grass, Bermuda Grass, Birch Tree, Box Elder/Maple Tree, Cat Dander, Cockroach (German), Common Short Ragweed, D. pteronyssinus (mites), D. farinae (mites), Dog Dander, Elm Tree, Hormodendrum (Cladosporium), Mouse Epithelium, Mountain Cedar (Juniper) Tree, Mucor racemosus, Nettle, Oak Tree, Pecan (White Hickory) Tree, Penicillium notatum, Pigweed, Sheep Sorrel (Dock), Timothy Grass, and IgE Serum Total.

Hotline History

N/A

CPT Codes

86003 x24; 82785

Components

Component Test Code* Component Chart Name LOINC
0050345 Immunoglobulin E 19113-0
0055001 Allergen, Fungi/Mold, A. alternata IgE 6020-2
0055003 Allergen, Tree, Box Elder/Maple Tree IgE 7155-5
0055006 Allergen, Animal, Cat Dander IgE 6833-8
0055007 Allergen, Tree, Mountain Cedar Tree IgE 6178-8
0055025 Allergen, Weed, Pigweed IgE 7604-2
0055032 Allergen, Grass, Timothy Grass IgE 6265-3
0055038 Allergen, Fungi/Mold, Hormodendrum IgE 6075-6
0055042 Allergen, Tree, Elm Tree IgE 6109-3
0055045 Allergen, Tree, Oak Tree IgE 6189-5
0055058 Allergen, Tree, Birch Tree IgE 15283-5
0055061 Allergen, Fungi/Mold, A. fumigatus IgE 6025-1
0055063 Allergen, Mites, D. pteronyssinus IgE 6096-2
0055064 Allergen, Mites, D. farinae IgE 6095-4
0055070 Allergen, Grass, Bermuda Grass IgE 6041-8
0055080 Allergen, Fungi/Mold, P. notatum IgE 6212-5
0055085 Allergen, Weed, Common/Short Ragweed IgE 6085-5
0055088 Allergen, Insect, Cockroach, German IgE 6078-0
0055145 Allergen, Tree, Pecan Tree IgE 6209-1
0055151 Allergen, Grass, Bahia IgE 6034-3
0055191 Allergen, Animal, Mouse Epithelium IgE 6179-6
0055442 Allergen, Fungi/Mold, M. racemosus IgE 6182-0
0099568 Allergen, Animal, Dog Dander IgE 6098-8
0099775 Allergen, Weed, Nettle IgE 6186-1
0099785 Allergen, Weed, Sheep Sorrel IgE 6244-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Allergen, Region 3 Respiratory Panel IgE, South Atlantic (GA, SC, N.FL)