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Liver Fibrosis - FibroMeter Vibration Controlled Transient Elastography (FibroMeter plus FibroScan VCTE)
3001379
Ordering Recommendation

Noninvasive assessment of liver fibrosis in patients with chronic viral hepatitis B or C (with or without HIV coinfection) and in patients with hepatic steatosis. Test can be performed only if the patient has a FibroScan score. Result based on both a panel of serum biomarkers (FibroMeter) and the FibroScan Vibration Controlled Transient Elastography (VCTE), a noninvasive, diagnostic ultrasound-based test that measures liver fibrosis.

Mnemonic
FIBRO VCTE
Methodology
Quantitative Nephelometry/Quantitative Enzymatic/Quantitative Spectrophotometry/Automated Cell Count/Electromagnetic Mechanical Clot Detection/Vibration Controlled Transient Elastography
Performed
Tue, Thu
Reported
1-5 days
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Patient must be 18 years of age or older. Platelet count should be performed on the EDTA whole blood sample at the client site within 3 days of submission for testing. 
Collect
Lavender (EDTA) or Pink (K2EDTA) AND Serum Separator Tube (SST) AND Light Blue (Sodium Citrate). 
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transport 3 mL serum in an ARUP Standard Transport Tube. (Min: 1.2 mL) AND Transport 1 mL platelet-poor citrated plasma in an ARUP Standard Transport Tube. (Min: 0.5 mL) Do not send the EDTA whole blood to ARUP. 
Storage/Transport Temperature
Serum: Frozen.
Plasma (citrated): CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered. 
Unacceptable Conditions
All required specimens not received. No platelet count received. VCTE performance date greater than 6 months from the specimen draw date and time. Hemolyzed specimens. 
Remarks
Include an automated platelet count. The Liver Stiffness result (in kPa) from the Fibroscan VCTE must be submitted with the samples. The performance date of the VCTE must also be submitted. 
Stability
Serum: Ambient: 8 hours; Refrigerated: Unacceptable; Frozen: 2 weeks
Plasma: Ambient: 24 hours; Refrigerated: Unacceptable; Frozen: 2 weeks 
Reference Interval
By report
Interpretive Data
Refer to report.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Delays in test performance may result if the VCTE result and date of performance is not included with the requisition.
Hotline History
View Hotline History
CPT Code(s)
83883; 84450; 82977 (Alt code: 81599)
Components
Component Test Code*Component Chart NameLOINC
2005664FibroMeter Platelet Count26515-7
2005666Fibrometer Prothrombin Index6302-4
2010928Aspartate Aminotransferase, FibroMeter1920-8
2010930Gamma Glutamyl Transferase, FibroMeter2324-2
2010932Alpha-2-Macroglobulin, FibroMeter1835-8
3001380EER Fibrometer VCTE Report11526-1
3001381FibroMeter VCTE Metavir Classification48794-2
3001382FibroMeter VCTE Interpretation48767-8
3001383FibroScan VCTE Liver Stiffness77615-3
3001384FibroMeter VCTE Score77616-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • FibroSure