Prion Markers (CJD), CSF
Ordering Recommendation
May aid in the diagnosis of Creutzfeldt-Jakob disease after other neurodegenerative conditions have been ruled out.
New York DOH Approval Status
Specimen Required
Patient must be 12 years of age or older.
CSF
The first 2 mL of CSF that flows from the tap should be discarded. Transfer 2 mL CSF to ARUP standard transport tubes and freeze immediately. (Min: 1 mL)
Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.
CRITICAL FROZEN
Completed requisition form required. Cloudy or pink specimens may result in partial results for some components.
Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: Indefinitely
Methodology
Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)/Qualitative Real-Time Quaking-Induced Conversion
Performed
Varies
Reported
7-17 days
Reference Interval
By report
Interpretive Data
Performed by non-ARUP Laboratory
Note
Repeat testing should be collected no sooner than 2 weeks following last encounter.
Hotline History
Hotline History
CPT Codes
86317; 0035U
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3001256 | Prion Markers (CJD), CSF | 19146-0 |
Aliases
- 14-3-3 Protein Tau, Total, CSF
- Creutzfeldt-Jakob Disease
- Human Prion Disease
- RT QuIC
NPDPSC