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14-3-3 Protein Tau, Total, CSF
3001255
Ordering Recommendation

May aid in the diagnosis of Creutzfeldt-Jakob disease after other neurodegenerative conditions have been ruled out.

Mnemonic
14-3-3 TAU
Methodology
Qualitative Western Blot/Quantitative Enzyme-Linked Immunosorbent Assay/Qualitative Real-Time Quaking-Induced Conversion
Performed
Varies
Reported
7-17 days
New York DOH Approval Status
This test is New York DOH approved.
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
CSF 
Specimen Preparation
The first 2 mL of CSF that flows from the tap should be discarded. Transfer 5 mL CSF to ARUP Standard Transport Tubes and freeze immediately. (Min: 2 mL) 
Storage/Transport Temperature
Frozen. 
Unacceptable Conditions
Specimens exposed to more than one freeze/thaw cycle. 
Remarks
Completed requisition form required. 
Stability
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: Indefinitely 
Reference Interval
By report
Interpretive Data


Note
Repeat testing should be collected no sooner than 2 weeks following last encounter.
Hotline History
View Hotline History
CPT Code(s)
Components
Component Test Code*Component Chart NameLOINC
300125614-3-3 Protein Tau, Total, CSF19146-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • CJD
  • Creutzfeldt-Jakob Disease
  • Human Prion Disease
  • RT QuIC

Performed at NPDPSC