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Marijuana Metabolite, Umbilical Cord Tissue, Qualitative
3000256
Ordering Recommendation

Detect in utero exposure to cannabis (marijuana) in neonates, consistent with maternal use during approximately the last trimester of pregnancy.

Mnemonic
THC QQQ CD
Methodology
Qualitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun-Sat
Reported
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
 
Collect
Umbilical Cord (At least 6 inches, approximately the length of an adult hand.) 
Specimen Preparation
Drain and discard any blood. Rinse the exterior of the cord segment with normal saline or sterile water. Pat the cord dry and transport at least 6 inches of umbilical cord in a routine urine collection cup or Security Kit for Meconium/Umbilical Drug Detection (ARUP supply #51548) available online through eSupply using ARUP Connect™ or by contacting ARUP Client Services at (800) 522-2787. (Min: 6 inches) 
Storage/Transport Temperature
Frozen. 
Unacceptable Conditions
Cords soaking in saline or other solutions. 
Remarks
 
Stability
Ambient: 3 days; Refrigerated: 2 weeks; Frozen: 1 year 
Reference Interval
Drugs/Drug ClassesCutoff Concentrations (ng/g)
THC-COOH0.2

Interpretive Data
Methodology: Qualitative Liquid Chromatography-Tandem Mass Spectrometry

This test is designed to detect and document exposure that occurred during approximately the last trimester of a full term birth, to a common cannabis (marijuana) metabolite. Alternative testing is available to detect other drug exposures. The pattern and frequency of drug(s) used by the mother cannot be determined by this test. A negative result does not exclude the possibility that a mother used drugs during pregnancy. Detection of drugs in umbilical cord tissue depends on extent of maternal drug use, as well as drug stability, unique characteristics of drug deposition in umbilical cord tissue, and the performance of the analytical method. Drugs administered during labor and delivery may be detected. Detection of drugs in umbilical cord tissue does not insinuate impairment and may not affect outcomes for the infant. Interpretive questions should be directed to the laboratory.

For medical purposes only; not valid for forensic use unless testing was performed within Chain of Custody process.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Absolute Minimum: 6 inches.
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CPT Code(s)
Components
Component Test Code*Component Chart NameLOINC
3000257THC-COOH, Cord, Qual61063-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases