Maternal T Cell Engraftment in SCID, Pre-Engraftment Specimen
Ordering Recommendation
Monitor engraftment of maternal T cells in patients with severe combined immunodeficiency (SCID) prior to allogenic stem cell transplantation.
New York DOH Approval Status
Specimen Required
Buccal brush
Collect 3-4 brush samples from patient and place in dry, sterile container for transport.
New York State Clients: 4-8 brush samples.
Ambient. Also acceptable: Refrigerated
Room Temperature: 1 week; Refrigerated: 1 month; Frozen: unacceptable
New York State Clients: Room Temperature: 7 days; Refrigerated: 14 days; Frozen: Unacceptable
Methodology
Polymerase Chain Reaction (PCR)/Fragment Analysis
Performed
Sun-Sat
Reported
5-9 days
Reference Interval
Interpretive Data
Refer to report.
Laboratory Developed Test (LDT)
Note
To complete Maternal T Cell Engraftment in SCID testing, samples should be collected to perform the following three tests: (1) A buccal brush collected from the patient for Maternal T Cell Engraftment in SCID, Pre-Engraftment Specimen (ARUP test code 2014694), used as a genetic baseline for the patient. (2) A peripheral blood sample from the biological mother for Maternal T Cell Engraftment in SCID, Maternal Specimen (ARUP test code 2014704), used as a genetic baseline for the mother. (3) A peripheral blood sample collected from the patient for Maternal T Cell Engraftment in SCID (ARUP test code 2014699). T cells isolated from the blood sample will be genotyped for comparison to the patient and biological mother baseline genotypes. If T-cell sorting is not completed on the blood sample before submission of Maternal T Cell Engraftment in SCID (ARUP test code 2014699), BMT Cell Isolation (ARUP test code 2005498) will be added to each order of Maternal T Cell Engraftment in SCID (ARUP test code 20146990). Additional charges apply for cell isolation.
Hotline History
CPT Codes
81265
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
2014695 | Specimen, Maternal Engraftment Pre | |
2014696 | Maternal Engraftment, Pre Interp | |
2014697 | Mat Engraftment, Pre, Informative Loci |
Aliases
- Maternal cell engraftment
- Maternal engraftment
- SCID
- SCID engraftment