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Tramadol and Metabolite, Quantitative, Serum or Plasma
2014686
Ordering Recommendation

Monitor patient adherence.

Mnemonic
TRAMADOL
Methodology
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed
Varies
Reported
3-10 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Plain Red, Lavender (EDTA), or Pink (K2EDTA). 
Collect
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.45 mL) 
Specimen Preparation
Refrigerated. Also acceptable: Room temperature or frozen. 
Storage/Transport Temperature
 
Unacceptable Conditions
Separator tubes. 
Remarks
 
Stability
Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: 11 months 
Reference Interval
By report
Interpretive Data
By report

Note
Peak serum levels are recommended when monitoring patients because the level in the blood drops so rapidly that many negative results are found at the trough. The peak occurs at 40 to 90 minutes post dose.
Hotline History
View Hotline History
CPT Code(s)
Components
Component Test Code*Component Chart NameLOINC
2014687Tramadol, Serum/Plasma12437-0
2014688O-Desmethyltramadol, Serum/Plasma73973-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • O-Desmethyltramadol
  • Ultram
  • Ultrex

Performed at National Medical Services (NMS)