Hepatitis C Virus (HCV) Genotype with Reflex to HCV NS5A Drug Resistance by Sequencing
2014598
Ordering Recommendation
Order before initiating treatment with NS5A inhibitors. Use to determine HCV type 1-6 after molecular confirmation of positive HCV screen. If genotype “1a or 1b” is determined, testing will reflex to HCV NS5A for genotype differentiation and drug resistance by sequencing.
Mnemonic
HCV RFX 5A
Methodology
Polymerase Chain Reaction/Sequencing
Performed
Sun-Sat
Reported
13-19 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
- Patient Preparation
- Collect
- Lavender (EDTA), Pink (K2EDTA), Plasma Preparation Tube (PPT), or Serum Separator Tube (SST).
- Specimen Preparation
- Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1.5 mL)
- Storage/Transport Temperature
- Frozen.
- Unacceptable Conditions
- Heparinized specimens.
- Remarks
- Stability
- Ambient: Unacceptable; Refrigerated: 72 hours; Frozen: 4 months
Reference Interval
By report
Interpretive Data
Refer to report.
Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Note
This test may be unsuccessful if the HCV RNA viral load is less than log 3.6 or 4000 IU/mL. If initial result is Type "1a or 1b", then HCV NS5A Drug Resistance by Sequencing will be added. Additional charges apply.
Hotline History
N/A
CPT Code(s)
87902; if reflexed, add 87902
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0055593 | HCV Genotype by Sequencing | 32286-7 |
Aliases