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Dermatomyositis Panel
2013991
Ordering Recommendation

May be useful for evaluation of patients with characteristic cutaneous manifestations of dermatomyositis with or without muscle weakness.

Mnemonic
DERM MYO
Methodology
Qualitative Immunoprecipitation/Qualitative Immunoblot
Performed
Mon, Tue, Thu, Fri
Reported
7-15 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum Separator Tube (SST). 
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transfer one 1 mL serum aliquots to ARUP Standard Transport Tubes. (Min: 0.5 mL/aliquot) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Hemolyzed, hyperlipemic, icteric, heat-treated or contaminated specimens. 
Remarks
 
Stability
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year 
Reference Interval
Test Number
Components
Reference Interval
 Mi-2 (nuclear helicase protein) AntibodyNegative
 P155/140 AntibodyNegative
 SAE1 (SUMO activating enzyme) AntibodyNegative
 MDA5 (CADM-140) AntibodyNegative
 NXP-2 (Nuclear matrix protein-2) AbNegative
 TIF-1 gamma (155 kDa) AntibodyNegative

Interpretive Data
Refer to report.

Compliance Statement D: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Antibodies: Mi-2, P155/140, SAE1, MDA5, NXP2, TIF1-gamma
Components
Component Test Code*Component Chart NameLOINC
2010852Mi-2 (nuclear helicase protein) Antibody18485-3
2010855P155/140 Antibody
2013962SAE1 (SUMO activating enzyme) Antibody
2013963NXP-2 (Nuclear matrix protein-2) Ab
2013964MDA5 (CADM-140) Antibody
2013965TIF-1 gamma (155 kDa) Antibody
2013996Dermatomyositis Interpretive Information48767-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases