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Heat Shock Protein 70, IgG by Immunoblot
2013590
Ordering Recommendation

Not recommended for evaluation of general hearing loss.

Mnemonic
HSP
Methodology
Qualitative Immunoblot
Performed
Sun, Tue, Thu
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum Separator Tube (SST) or Plain Red. 
Specimen Preparation
Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Urine or plasma. Heat inactivated and contaminated specimens. 
Remarks
 
Stability
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year 
Reference Interval
Negative
Interpretive Data
The presence of HSP70 IgG antibodies may be useful in predicting corticosteroid responsiveness in a subset of patients with autoimmune inner ear disease (AIED) characterized by idiopathic rapidly progressive sensorineural hearing loss (SNHL). HSP70 IgG antibodies are also associated with a number of autoimmune diseases and have also been reported in apparently healthy individuals. A negative result does not rule out response to treatment or to a diagnosis of AIED.

Compliance Statement D: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Components
Component Test Code*Component Chart NameLOINC
2013591Heat Shock Protein 70, IgG by Immunoblot43597-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases