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Meningitis/Encephalitis Panel by PCR
2013305
Ordering Recommendation

Use to rapidly detect a panel of common viruses, bacteria, and fungi associated with meningitis and encephalitis. Do NOT use as a replacement for CSF bacterial and/or fungal culture and Cryptococcal antigen testing for at-risk patients. A negative result does not exclude a diagnosis of meningitis or encephalitis due to infection.

Mnemonic
MEFAP
Methodology
Qualitative Polymerase Chain Reaction
Performed
Sun-Sat
Reported
Within 24 hours
N/A
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
N/A 
Collect
CSF 
Specimen Preparation
Transfer 0.5 mL CSF to a sterile ARUP Standard Transport Tube (ARUP supply #43115) available online through eSupply using ARUP Connect or contact ARUP Client Services at (800) 522-2787. (Min: 0.25 mL) Do not centrifuge. 
Storage/Transport Temperature
Refrigerated 
Unacceptable Conditions
N/A 
Remarks
N/A 
Stability
Ambient: 24 hours; Refrigerated: 1 week; Frozen: Unacceptable 
Reference Interval
Not Detected
Interpretive Data
The meningitis/encephalitis panel is NOT a replacement for CSF bacterial and/or fungal culture and Cryptococcal antigen testing for at-risk patients. Non-K1 E. coli serotypes and non-encapsulated strains of Neisseria meningitidis are NOT detected. The panel does NOT differentiate active from latent herpes virus infections. Test results should be interpreted in the context of host factors and other laboratory information.

Note
This panel includes Cryptococcus neoformans/gattii, Cytomegalovirus (CMV), Enterovirus, Escherichia coli K1, Haemophilus influenzae, Herpes simplex virus 1(HSV-1), Herpes simplex virus 2(HSV-2), Human herpesvirus 6 (HHV-6), Human parechovirus, Listeria monocytogenes, Neisseria meningitidis, Streptococcus agalactiae, Streptococcus pneumoniae, Varicella-zoster virus (VZV).
Components
Component Test Code*Component Chart NameLOINC
2013306Cytomegalovirus by PCR82189-2
2013307Cryptococcus neoformans/gattii by PCR82181-9
2013308Escherichia coli K1 by PCR82182-7
2013309Enterovirus by PCR82194-2
2013310Haemophilus influenzae by PCR82183-5
2013311Human herpesvirus 6 by PCR82192-6
2013312Herpes simplex virus 1 by PCR82190-0
2013313Herpes simplex virus 2 by PCR82191-8
2013314Listeria monocytogenes by PCR82184-3
2013315Neisseria meningitidis by PCR82185-0
2013316Human parechovirus by PCR82193-4
2013317Streptococcus agalactiae by PCR82186-8
2013318Varicella zoster virus by PCR82188-4
2013319Streptococcus pneumoniae by PCR82187-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Film Array Panel