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Inflammatory Bowel Disease Differentiation Panel
2013270
Ordering Recommendation

May be a useful tool for distinguishing ulcerative colitis (UC) from Crohn disease (CD) in patients with suspected inflammatory bowel disease.

Mnemonic
IBD PAN
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Indirect Fluorescent Antibody
Performed
Sat-Sun
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
N/A 
Collect
Serum Separator Tube (SST). 
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transfer 1.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.6 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens. 
Remarks
N/A 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
Test Number
Components
Reference Interval
 S. cerevisiae Antibody, IgG
20.0 Units or lessNegative
20.1-24.9 UnitsEquivocal
25.0 Units or greaterPositive

 S. cerevisiae Antibody, IgA
20.0 Units or lessNegative
20.1-24.9 UnitsEquivocal
25.0 Units or greaterPositive

0050811Anti-Neutrophil Cytoplasmic Antibody, IgGLess than 1:20: Not significant

Interpretive Data
Refer to report.

Note
This test may be a useful tool for distinguishing ulcerative colitis (UC) from Crohn disease (CD) in patients with suspected inflammatory bowel disease. If the ANCA screen detects antibodies at a 1:20 dilution or greater, then a titer to end point will be added. Additional charges apply. ANCA IFA is simultaneously tested on ethanol- and formalin-fixed slides to allow differentiation of C- and P-ANCA patterns.
CPT Code(s)
86671 x2; 86255; if reflexed, add 86256
Components
Component Test Code*Component Chart NameLOINC
0050562S. cerevisiae Antibody, IgG47321-5
0050563S. cerevisiae Antibody, IgA47320-7
0050811Anti-Neutrophil Cytoplasmic Ab, IgG29967-7
2013271EER Inflammatory Bowel Disease Panel
2013448Inflammatory Bowel Disease Interp
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • ASCA
  • atypical p-ANCA Ab
  • atypical p-ANCA IgG
  • Atypical perinuclear anticytoplasmic neutrophil Ab
  • Atypical perinuclear anticytoplasmic neutrophil IgG
  • IBD Differentiation Profile
  • S. cerevisiae Ab
  • Saccharomyces cerevisiae Antibody