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Human Herpesvirus 8 (HHV-8) by Quantitative PCR
2013089
Ordering Recommendation

Detect and quantify herpesvirus 8 (HHV-8).

Mnemonic
HHV8 QNT
Methodology
Quantitative Polymerase Chain Reaction
Performed
Mon, Thu
Reported
2-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA), Pink (K2 EDTA), or Serum Separator Tube (SST). 
Specimen Preparation
Separate serum or plasma from cells. Transport 1 mL plasma, serum, or whole blood in a sterile container. (Min: 0.5 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Heparinized specimens. 
Remarks
Specimen source required. 
Stability
Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year 
Reference Interval
Not detected
Interpretive Data
The quantitative range of this assay is 3.8-8.8 log copies/mL (6,670-667,000,000 copies/mL).

A negative result (less than 3.8 log copies/mL or less than 6,670 copies/mL) does not rule out the presence of PCR inhibitors in the patient specimen or HHV8 DNA concentrations below the level of detection of the test. Inhibition may also lead to underestimation of viral quantitation.

No international standard is currently available for calibration of this assay. Caution should be taken when interpreting results generated by different assay methodologies.

Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
The limit of quantification for this DNA test is 3.8 log copies/mL (6,670 copies/mL). If the test DID NOT DETECT the virus, the test result will be reported as "< 3.8 log copies/mL (< 6,670 copies/mL)." If the test DETECTED the presence of the virus but was not able to accurately quantify the number of copies, the test result will be reported as "Not Quantified."
CPT Code(s)
87799
Components
Component Test Code*Component Chart NameLOINC
2013090HHV8 by Quantitative PCR, Source31208-2
2013091HHV8 by Quantitative PCR, Copy/mL49404-7
2013092HHV8 by Quantitative PCR, Log copy/mL
2013093HHV8 by Quantitative PCR, Interp39083-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • HHV8
  • Viral load monitoring, Kaposi's sarcoma herpes virus (KSHV)