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Non-Criteria Antiphospholipid Syndrome (APS) (aPa, aPc, aPe, aPg, aPi) Antibodies Extended Panel
2012730
Ordering Recommendation

Not a recommended test. Test has limited clinical value in assessing risk for pregnancy-related morbidity and thrombosis in antiphospholipid syndrome (APS).

Mnemonic
NCAPS EXT
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Fri
Reported
1-8 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube (SST). 
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.9 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Heat-inactivated, grossly hemolyzed, icteric, or lipemic specimens. 
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
Test NumberComponentsReference Interval
2007610Phosphatidic Acid Antibodies, IgG, IgM, and IgA0-11 U/mL: Normal
12-18 U/mL: Equivocal. Suggest repeat testing in 4-6 weeks or consider antibody testing for cardiolipin IgG and IgM, beta-2 glycoprotein 1 IgG and IgM and lupus anticoagulant.
19 U/mL or greater:  Positive
0051590Phosphatidylcholine Antibodies, IgG, IgM and IgA0-11 U/mL: Normal
12-18 U/mL: Equivocal. Suggest repeat testing in 4-6 weeks or consider antibody testing for cardiolipin IgG and IgM, beta-2 glycoprotein 1 IgG and IgM and lupus anticoagulant.
19 U/mL or greater: Positive
0051622Phosphatidylethanolamine Antibodies, IgG, IgM and  IgA0-11 U/mL: Normal
12-18 U/mL: Equivocal. Suggest repeat testing in 4-6 weeks or consider antibody testing for cardiolipin IgG and IgM, beta-2 glycoprotein 1 IgG and IgM and lupus anticoagulant.
19 U/mL or greater: Positive
0051623Phosphatidylglycerol Antibodies, IgG, IgM and IgA0-11 U/mL: Normal
12-18 U/mL: Equivocal. Suggest repeat testing in 4-6 weeks or consider antibody testing for cardiolipin IgG and IgM, beta-2 glycoprotein 1 IgG and IgM and lupus anticoagulant.
19 U/mL or greater: Positive
0051624Phosphatidylinositol Antibodies, IgG, IgM and IgA0-11 U/mL: Normal
12-18 U/mL: Equivocal. Suggest repeat testing in 4-6 weeks or consider antibody testing for cardiolipin IgG and IgM, beta-2 glycoprotein 1 IgG and IgM and lupus anticoagulant.
19 U/mL or greater: Positive

Interpretive Data


Compliance Statement D: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Components
Component Test Code*Component Chart NameLOINC
0051591Phosphatidylcholine Ab, IgG14008-7
0051592Phosphatidylcholine Ab, IgM14009-5
0051593Phosphatidylcholine Ab, IgA14010-3
0051601Phosphatidylethanolamine Antibody IgA13078-1
0051602Phosphatidylethanolamine Antibody IgG13076-5
0051603Phosphatidylethanolamine Antibody IgM13077-3
0051604Phosphatidylglycerol Antibody IgA13081-5
0051605Phosphatidylglycerol Antibody IgG13079-9
0051606Phosphatidylglycerol Antibody IgM13080-7
0051607Phosphatidylinositol Antibody IgA13084-9
0051608Phosphatidylinositol Antibody IgG13082-3
0051609Phosphatidylinositol Antibody IgM13083-1
2007604Phosphatidic Acid Antibody, IgM13071-6
2007606Phosphatidic Acid Antibody, IgG13070-8
2007608Phosphatidic Acid Antibody, IgA13072-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • ACA and non-criteria APS panel
  • aCL and non-criteria APS
  • aCL and non-criteria APS panel
  • APS aCL and non-criteria panel