Ordering Recommendation

The intended use of this test is pre-transplant allele matching. Do not use for HLA-related disease screening or diagnosis (eg, celiac disease, narcolepsy, rheumatologic diseases).

New York DOH Approval Status

Testing is not New York state approved. Specimens from New York clients will be sent out to a New York state-approved laboratory.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA). Also acceptable: yellow (ACD Solution A).

Specimen Preparation

Transport 4 mL whole blood in original container. (Min: 1 mL)
Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Yellow (ACD Solution B) specimens. Clotted, grossly hemolyzed, or heparinized specimens.

Remarks
Stability

Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable

Methodology

Polymerase Chain Reaction/Massively Parallel Sequencing

Performed

Varies

Reported

10-13 days

Reference Interval

By Report

Interpretive Data



Compliance Category

Performed by non-ARUP Laboratory

Note

Hotline History

N/A

CPT Codes

81382

Components

Component Test Code* Component Chart Name LOINC
2012495 HLA-DRB1*, Class II - Locus, Allele 1 19146-0
2012496 HLA-DRB1*, Class II - Locus, Allele 2 19146-0
2012497 HLA-DRB1 by NGS, Interpretation 19146-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

HLA-DRB1 by Next Generation Sequencing

Children’s Hospital of Philadelphia