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HLA-DRB1 by Next Generation Sequencing
2012494
Ordering Recommendation

The intended use of this test is pre-transplant allele matching. Do not use for HLA-related disease screening or diagnosis (eg, celiac disease, narcolepsy, rheumatologic diseases).

Mnemonic
HLA DRB1
Methodology
Polymerase Chain Reaction/Massive Parallel Sequencing
Performed
Varies
Reported
10-13 days
N/A
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA). Also acceptable: yellow (ACD Solution A). 
Specimen Preparation
Transport 4 mL whole blood in original container. (Min: 1 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Yellow (ACD Solution B) specimens. Clotted, grossly hemolyzed, or heparinized specimens. 
Remarks
 
Stability
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable 
Reference Interval
By Report
Interpretive Data


Components
Component Test Code*Component Chart NameLOINC
2012495HLA-DRB1*, Class II - Locus, Allele 1
2012496HLA-DRB1*, Class II - Locus, Allele 2
2012497HLA-DRB1 by NGS, Interpretation
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases

Performed at Children’s Hospital of Philadelphia