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JAK2 Gene, V617F Mutation, Qualitative with Reflex to JAK2 Exon 12 Mutation Analysis by PCR
2012085
Ordering Recommendation

Use when diagnosis of polycythemia vera (PV) is suspected.

Mnemonic
PV RFLX
Methodology
Polymerase Chain Reaction
Performed
DNA Isolation: Sun-Sat
Assay: Mon, Wed, Fri
Reported
7-10 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA) OR bone marrow (EDTA). 
Specimen Preparation
Do not freeze. Transport 5 mL whole blood. (Min: 1 mL) OR Transport 3 mL bone marrow. (Min: 1 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Serum. Specimens collected in anticoagulants other than EDTA. Clotted or grossly hemolyzed specimens. 
Remarks
 
Stability
Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable 
Reference Interval
Interpretive Data
Refer to report.

Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
If JAK2 V617F is reported as "Not Detected" then JAK2 Exon 12 Mutation Analysis will be added. Additional charges apply.
CPT Code(s)
81270: if reflexed add 81403
Components
Component Test Code*Component Chart NameLOINC
0051245JAK2 Gene, V617F Mutation, Qualitative43399-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases