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Bruton Tyrosine Kinase (BTK) Protein Expression by Flow Cytometry
2012002
Ordering Recommendation

Preferred test for initial screening for individuals with clinical suspicion of x-linked agammaglobulinemia/hypogammaglobulinemia.

Mnemonic
BTK FLOW
Methodology
Qualitative Flow Cytometry
Performed
Sun-Sat
Reported
1-3 days
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Green (sodium or lithium Heparin). 
Specimen Preparation
Transport 4 mL whole blood. (Min: 0.5 mL) 
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated. 
Unacceptable Conditions
Clotted or hemolyzed specimens. 
Remarks
Specimen must be analyzed within 72 hours of collection. 
Stability
Ambient: 72 hours; Refrigerated: 72 hours; Frozen: Unacceptable 
Reference Interval
Normal
Interpretive Data


Compliance Statement A: For laboratory developed tests using a manufacturer labeled ASR as the reagent providing the specificity of the assay. Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.

Note
Hotline History
N/A
Components
Component Test Code*Component Chart NameLOINC
2012003Bruton Tyrosine Kinase (BTK)
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Agammaglobulinemia
  • Btk (Bruton's Tyrosine Kinase)
  • Tyrosine Kinase
  • X-Linked Agammaglobulinemia (XLA)
  • XLA (X-Linked Agammaglobulinemia)