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Bruton Tyrosine Kinase (BTK) Protein Expression by Flow Cytometry
2012002
Ordering Recommendation

Preferred test for initial screening for individuals with clinical suspicion of x-linked agammaglobulinemia/hypogammaglobulinemia.

Mnemonic
BTK FLOW
Methodology
Qualitative Flow Cytometry
Performed
Sun-Sat
Reported
1-3 days
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Green (sodium or lithium Heparin). 
Specimen Preparation
Transport 4 mL whole blood. (Min: 0.5 mL) 
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated. 
Unacceptable Conditions
Clotted or hemolyzed specimens. 
Remarks
Specimen must be analyzed within 72 hours of collection. 
Stability
Ambient: 72 hours; Refrigerated: 72 hours; Frozen: Unacceptable 
Reference Interval
Normal
Interpretive Data


Compliance Statement A: Analyte specific reagents (ASR) are used in many laboratory tests necessary for standard medical care and generally do not require U.S. Food and Drug Administration (FDA) approval or clearance. This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. This test should not be regarded as investigational or for research use.

Note
CPT Code(s)
86356 x3
Components
Component Test Code*Component Chart NameLOINC
2012003Bruton Tyrosine Kinase (BTK)
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Agammaglobulinemia
  • Btk (Bruton's Tyrosine Kinase)
  • Tyrosine Kinase
  • X-Linked Agammaglobulinemia (XLA)
  • XLA (X-Linked Agammaglobulinemia)