Human Papillomavirus (HPV), High Risk by PCR, ThinPrep
Ordering Recommendation

FDA-approved test for routine cervical cancer screening in combination with cervical cytology (Pap smear) for women ≥30 years. Follow-up test for abnormal cytology results in women ≥21 years. 

Qualitative Polymerase Chain Reaction
Mon, Wed, Fri
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Cervical, anal or vaginal specimens with brush or spatula from ThinPrep kit and place in PreservCyt Media. 
Specimen Preparation
Transfer 3 mL to an ARUP Standard Transport Tube. (Min 1.5 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Bloody or dark brown specimens. Specimens in any media other than indicated above. 
Specimen source required. 
Ambient: 6 months; Refrigerated: 6 month; Frozen: Unacceptable 
Reference Interval
Interpretive Data
This test amplifies DNA of 14 high-risk HPV types associated with cervical cancer and its precursor lesions (HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68). Sensitivity may be affected by specimen collection methods, stage of infection, and the presence of interfering substances. Results should be interpreted in conjunction with other available laboratory and clinical data. A negative high-risk HPV result does not exclude the possibility of future cytologic HSIL or underlying CIN2-3 or cancer.

This test is intended for medical purposes only and is not valid for the evaluation of suspected sexual abuse or for other forensic purposes. HPV testing should not be used for screening or management of atypical squamous cells of undetermined significance (ASCUS) in women under age 21.

Component Test Code*Component Chart NameLOINC
0060752HPV Source31208-2
2011948HPV High Risk by PCR, ThinPrep49896-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • HPV High Risk
  • HPV HR ThinPrep
  • Human papilloma virus