May aid in the diagnosis of chikungunya viral infection during acute phase of disease (>5 days after symptom onset). In endemic regions, recommend co-testing for dengue and Zika virus because clinical picture of these diseases is similar.
- Patient Preparation
- Serum separator tube.
- Specimen Preparation
- Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute or convalescent."
- Storage/Transport Temperature
- Unacceptable Conditions
- Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
- After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
|Test Code||Component||Reference Interval|
|2011808||Chikungunya Antibody, IgG||0.90 Index or less||Negative: No significant level of Chikungunya IgG antibody detected.|
|0.91-1.09 Index||Equivocal: Questionable presence of Chikungunya IgG antibody detected. Repeat testing in 10-14 days may be helpful.|
|1.10 Index or greater||Positive: Chikungunya IgG antibody detected; suggests current or past infection.|
|2011810||Chikungunya Antibody, IgM||0.90 Index or less||Negative: No significant level of Chikungunya IgM antibody detected.|
|0.91-1.09 Index||Equivocal: Questionable presence of Chikungunya IgM antibody detected. Repeat testing in 10-14 days may be helpful.|
|1.10 Index or greater||Positive: Chikungunya IgM antibody detected.|
|Component Test Code*||Component Chart Name||LOINC|
|2011809||Chikungunya Antibody, IgG||56128-2|
|2011811||Chikungunya Antibody, IgM||56130-8|