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Microsporidia by PCR
2011626
Ordering Recommendation

Preferred test to diagnose Microsporidia in immunocompromised patients with persistent diarrhea if Encephalitozoon spp (E. intestinalis/E. hellem/E. cuniculi) or E. bieneusi is the suspected infectious agent.

Mnemonic
MICROSPCR
Methodology
Qualitative Polymerase Chain Reaction
Performed
Tue, Thu, Sat
Reported
2-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Stool. 
Specimen Preparation
Transfer 1 mL stool to an unpreserved stool transport vial (ARUP supply #40910). Available online through eSupply using ARUP Connect® or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL) 
Storage/Transport Temperature
Frozen. 
Unacceptable Conditions
Specimens in Viral Transport Media. Stool in formalin. 
Remarks
Additional information required: Specimen source 
Stability
Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: 2 weeks 
Reference Interval
Interpretive Data
A negative result does not rule out the presence of PCR inhibitors in the patient specimen or test-specific nucleic acid in concentrations below the level of detection by this test.

Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
This test detects and speciates Enterocytozoon bieneusi. The nucleic acid from Encephalitozoon intestinalis, Encephalitozoon hellem, and Encephalitozoon cuniculi will be detected by this test but cannot be differentiated.
Components
Component Test Code*Component Chart NameLOINC
2011627Microsporidia by PCR, Source
2011628Enterocytozoon bieneusi by PCR
2011629Encephalitozoon species by PCR
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Encephalitozoon cuniculi
  • Encephalitozoon hellem
  • Encephalitozoon intestinalis
  • Enterocytozoon bieneusi