Microsporidia by PCR
Ordering Recommendation

Preferred test to diagnose Microsporidia in immunocompromised patients with persistent diarrhea if Encephalitozoon spp (E. intestinalis/E. hellem/E. cuniculi) or E. bieneusi is the suspected infectious agent.

Qualitative Polymerase Chain Reaction
Tue, Thu, Sat
2-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Specimen Preparation
Transfer 1 mL stool to an unpreserved stool transport vial (ARUP supply #40910). Available online through eSupply using ARUP Connect® or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Specimens in Viral Transport Media. Stool in formalin. 
Additional information required: Specimen source 
Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: 2 weeks 
Reference Interval
Interpretive Data
A negative result does not rule out the presence of PCR inhibitors in the patient specimen or test-specific nucleic acid in concentrations below the level of detection by this test.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

This test detects and speciates Enterocytozoon bieneusi. The nucleic acid from Encephalitozoon intestinalis, Encephalitozoon hellem, and Encephalitozoon cuniculi will be detected by this test but cannot be differentiated.
Hotline History
Component Test Code*Component Chart NameLOINC
2011627Microsporidia by PCR, Source31208-2
2011628Enterocytozoon bieneusi by PCR41443-3
2011629Encephalitozoon species by PCR
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Encephalitozoon cuniculi
  • Encephalitozoon hellem
  • Encephalitozoon intestinalis
  • Enterocytozoon bieneusi