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Thiocyanate, Serum or Plasma
2011575
Ordering Recommendation

Therapeutic monitoring in patients receiving sodium nitroprusside therapy. Screen for thiocyanate poisoning.

Mnemonic
THIO SP
Methodology
Quantitative Colorimetry
Performed
Mon, Fri
Reported
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Plain Red, Lavender (K2EDTA), Lavender (K3EDTA), or Pink (K2EDTA). 
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Whole blood. Gel Separator Tubes, Light Blue (Sodium Citrate), or Yellow (SPS or ACD Solution). 
Remarks
Please indicate in the supplied fields:
1.  Dose - List drug amount and include the units of measure
2.  Route - List the route of administration (IV, oral, etc.)
3.  Dose Frequency - Indicate how often the dose is administered (per day, per week, as needed, etc.)
4.  Type of Draw - Indicate the type of blood draw (Peak, Trough, Random, etc.) 
Stability
Ambient: 5 days; Refrigerated: 5 days; Frozen: 5 days 
Reference Interval
Nonsmoker:  1-4 µg/mL
Smoker:  3-12 µg/mL
Toxic:  Greater than 50 µg/mL
Values seen with nitroprusside therapy:  6-29 µg/mL
Interpretive Data
The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration.

Note
N/A
CPT Code(s)
84430
Components
Component Test Code*Component Chart NameLOINC
2011576Thiocyanate Dose
2011577Thiocyanate Dose Frequency
2011578Thiocyanate Route
2011579Thiocyanate Type of Draw
2011580Thiocyanate, Ser/Pla
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Nipride, Metabolite of
  • Nitropress Administration
  • Nitroprusside Metabolite
  • Rhodanide
  • Sodium Nitroprusside