Cadmium, Random Urine
Ordering Recommendation
Useful in the assessment of chronic exposure and determination of cadmium body burden. For acute exposure, Cadmium, Blood (0099675) is preferred.
New York DOH Approval Status
Specimen Required
Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and nonessential over-the-counter medications (upon the advice of their physician). High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended.
Random urine.
Transfer an 8 mL aliquot to ARUP Trace Element-Free Transport Tubes (ARUP supply #43116), available online through eSupply using ARUP Connect(TM) or contact ARUP Client Services at 800-522-2787. (Min: 1 mL)
Refrigerated. Also acceptable: Room temperature or frozen.
Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with MRI studies). Acid preserved urine.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 1 year
Methodology
Quantitative Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
Performed
Sun-Sat
Reported
1-5 days
Reference Interval
| Components |
Reference Interval |
|---|---|
| Cadmium, Urine - per volume | 0.0-1.0 µg/L |
| Cadmium Rnd Urn ratio/CRT nonoccupation | 0.0-3.2 µg/gCRT |
Interpretive Data
Urine cadmium concentrations can be used to assess cadmium body burden. In chronic exposures, the kidneys are the primary target organ. Symptoms associated with cadmium toxicity vary based upon route of exposure and may include tubular proteinuria, fever, headache, dyspnea, chest pain, conjunctivitis, rhinitis, sore throat and cough. Ingestion of cadmium in high concentration may cause vomiting, diarrhea, salivation, cramps, and abdominal pain.
Elevated results may be due to skin or collection-related contamination, including the use of collection containers that are not certified to be trace element-free. If an elevated result is suspected to be due to contamination, confirmation with a second specimen collected in a certified trace element-free container is recommended.
Methodology: Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
Standard
Note
Hotline History
CPT Codes
82300
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0020207 | Creatinine, Urine - per volume | 35674-1 |
| 0025038 | Cadmium, Urine - ratio to CRT | 13828-9 |
| 0025042 | Cadmium, Urine - per volume | 5611-9 |
Aliases
- Cd
- CDU
















