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Carisoprodol and Meprobamate, Serum or Plasma, Quantitative
2011450
Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Mnemonic
CARIS SP
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Mon, Fri
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum Pre-dose (Trough) Draw - At a Steady State Concentration or Plasma Pre-dose (Trough) Draw - At a Steady State Concentration in Plain Red, Lavender (K2EDTA), Lavender (K3EDTA), or Pink (K2EDTA). 
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Whole blood. Gel Separator Tubes, Light Blue (Sodium Citrate), or Yellow (SPS or ACD Solution). 
Remarks
Please indicate in the supplied fields:
1.  Dose - List drug amount and include the units of measure
2.  Route - List the route of administration (IV, oral, etc.)
3.  Dose Frequency - Indicate how often the dose is administered (per day, per week, as needed, etc.)
4.  Type of Draw - Indicate the type of blood draw (Peak, Trough, Random, etc.) 
Stability
Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 months 
Reference Interval
Test Number
Components
Reference Interval
 Carisoprodol, Serum or PlasmaLess than 8.0 µg/mL
Toxic: Greater than or equal to 8.0 µg/mL
 Meprobamate, Serum or Plasma
Dose-Related Range5.0-20.0 µg/mL
ToxicGreater than 40.0 µg/mL


Interpretive Data
The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration.Adverse effects may include drowsiness, dizziness and headache.

Note
CPT Code(s)
80369 (Alt code: G0480)
Components
Component Test Code*Component Chart NameLOINC
2011451Carisoprodol Dose
2011452Carisoprodol Dose Frequency
2011453Carisoprodol Route
2011454Carisoprodol Type of Draw
2011455Carisoprodol, Serum or Plasma3437-1
2011456Meprobamate, Serum or Plasma3753-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Carisoprodol
  • Carisoprodol and Metabolite
  • Rela
  • Sodol
  • Soma
  • Soma Compound
  • Soprodol
  • Soridol
  • Urine
  • Vanadom