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Carisoprodol and Meprobamate, Serum or Plasma, Quantitative
2011450
Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Mnemonic
CARIS SP
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun, Tue, Thu
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum Pre-dose (Trough) Draw - At a Steady State Concentration or Plasma Pre-dose (Trough) Draw - At a Steady State Concentration in Plain Red, Lavender (K2EDTA), Lavender (K3EDTA), or Pink (K2EDTA). 
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Whole blood. Gel Separator Tubes, Light Blue (Sodium Citrate), or Yellow (SPS or ACD Solution). 
Remarks
 
Stability
Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 months 
Reference Interval
Test Number
Components
Reference Interval
 Carisoprodol, Serum or PlasmaLess than 8.0 µg/mL
Toxic: Greater than or equal to 8.0 µg/mL
 Meprobamate, Serum or Plasma
Dose-Related Range5.0-20.0 µg/mL
ToxicGreater than 40.0 µg/mL


Interpretive Data
The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration. Adverse effects may include drowsiness, dizziness and headache.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
View Hotline History
CPT Code(s)
Components
Component Test Code*Component Chart NameLOINC
2011455Carisoprodol, Serum or Plasma3437-1
2011456Meprobamate, Serum or Plasma3753-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Carisoprodol
  • Carisoprodol and Metabolite
  • Equanil
  • Meprospan
  • Miltown
  • Rela
  • Sodol
  • Soma
  • Soma Compound
  • Soprodol
  • Soridol
  • Urine
  • Vanadom