Ordering Recommendation

Use to monitor disease in patients diagnosed with epidermolysis bullosa acquisita (EBA) or bullous lupus erythematosus with increased IgG type VII collagen antibody levels.

For initial diagnosis, including discrimination among various immunobullous diseases, and assessment of disease progression/changes and intermittent monitoring, the Immunobullous Disease Antibody Panel (3001409) or Basement Membrane Zone Antibody Panel (3001410) is preferred.

For more information about components, methodology, and specimen type, see the ARUP Immunobullous Disease Testing Comparison tool.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Plain red or serum separator tube (SST).

Specimen Preparation

Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed or lipemic specimens. Plasma.

Remarks
Stability

Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Varies

Reported

7-14 days

Reference Interval

By report

Interpretive Data

Refer to report

Compliance Category

Performed by non-ARUP Laboratory

Note

For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.

Hotline History

N/A

CPT Codes

83516

Components

Component Test Code* Component Chart Name LOINC
2010906 Collagen Type VII Antibody IgG by ELISA
2010907 EER Collagen Type VII Ab IgG, by ELISA
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • bullous lupus erythematosus
  • Collagen Type VII Antibody IgG by ELISA
  • dermal basement membrane zone antibodies on split skin substrate
  • epidermolysis bullosa acquisita
  • salt-split skin floor antibodies
  • type VII collagen antibodies
Collagen Type VII Antibody, IgG by ELISA