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Antiviral Susceptibility, Herpes Simplex Virus, Acyclovir
2010866
Ordering Recommendation

Detect herpes simplex virus (HSV) resistance to acyclovir.

Mnemonic
HSVSUS ACV
Methodology
Cell Culture, Susceptibility
Performed
Wed
Reported
2-3 weeks
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Isolate from cell culture (3-4+ positivity). 
Specimen Preparation
Isolate from cell culture (3-4+ positivity). Place each specimen in an individually sealed bag. 
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated and frozen on dry ice. 
Unacceptable Conditions
 
Remarks
 
Stability
Ambient: 48 hours; Refrigerated: 72 hours; Frozen at -70°C: 1 month 
Reference Interval
Less than 2 µg/mL
Interpretive Data
A value of greater than or equal to 2 µg/mL suggests resistance.

Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
A processing fee will be billed for isolates that fail to grow to 3-4+ positivity as indicated in the specimen requirements. For specimens other than isolates (swabs) refer to Herpes Simplex Virus Culture (Test Number 0065005). 
Components
Component Test Code*Component Chart NameLOINC
2010868Acyclovir Interpretation73574-6
2010978Acyclovir IC50 Value9416-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Acyclovir Resistance HSV
  • Drug Resistance
  • Herpes Simplex Types 1 and 2 virus Phenotyping
  • Phenotyping for Acyclovir
  • Zovirax Resistance