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Antiviral Susceptibility, Herpes Simplex Virus, Acyclovir
2010866
Ordering Recommendation

Detect herpes simplex virus (HSV) resistance to acyclovir.

Mnemonic
HSVSUS ACV
Methodology
Cell Culture, Susceptibility
Performed
Wed
Reported
2-3 weeks
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Isolate from cell culture (3-4+ positivity). 
Specimen Preparation
Isolate from cell culture (3-4+ positivity). Place each specimen in an individually sealed bag. 
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated and frozen on dry ice. 
Unacceptable Conditions
 
Remarks
 
Stability
Ambient: 48 hours; Refrigerated: 72 hours; Frozen at -70°C: 1 month 
Reference Interval
Less than 2 µg/mL
Interpretive Data
A value of greater than or equal to 2 µg/mL suggests resistance.

Note
A processing fee will be billed for isolates that fail to grow to 3-4+ positivity as indicated in the specimen requirements. For specimens other than isolates (swabs) refer to Herpes Simplex Virus Culture (Test Number 0065005). 
CPT Code(s)
87252; 87253
Components
Component Test Code*Component Chart NameLOINC
2010868Acyclovir Interpretation73574-6
2010978Acyclovir IC50 Value9416-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Acyclovir Resistance HSV
  • Drug Resistance
  • Herpes Simplex Types 1 and 2 virus Phenotyping
  • Phenotyping for Acyclovir
  • Zovirax Resistance