Antimicrobial Susceptibility - Carbapenem Resistance Confirmation by PCR (INACTIVE as of 05/15/17: Refer to 2014277)
Ordering Recommendation

Detect the presence of genes (blaKPC and blaNDM) responsible for resistance to carbapaenem and other beta-lactam antibiotics.

Qualitative Polymerase Chain Reaction
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Actively growing Enterobacteriaceae, Pseudomonas aeruginosa, Acinetobacter in pure culture or rectal/fecal swab. 
Specimen Preparation
Transport sealed container with pure culture on agar slant/bacterial transport media or rectal/fecal swab. Place each specimen in an individually sealed bag. 
Storage/Transport Temperature
Room temperature. 
Unacceptable Conditions
Mixed cultures or non-viable organisms. 
Isolate identification and specimen source required. 
Ambient: 1 week; Refrigerated: 1 week; Frozen: Unacceptable 
Reference Interval
Interpretive Data
This test detects the genes blaKPC and blaNDM in gram negative enteric bacteria. These genes encode enzymes (Klebsiella pneumoniae carbapenemase [KPC] and New Delhi metallo-beta-lactamase [NDM], respectively) causing resistance to carbapenem and other beta-lactam antibiotics.

This test is performed pursuant to an agreement with Roche Molecular Systems, Inc.

Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

An additional processing fee will be billed for all organisms not submitted in pure culture, as indicated in the specimen requirements.

If species identification is not provided, identification will be performed at ARUP. Additional charges apply.
Component Test Code*Component Chart NameLOINC
2008462Suscept, Carbapenem Resistance by PCR
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • carbapenem-resistance
  • carbapenems
  • Enterobacteriaceae
  • Klebsiella pneumonia carbapenemase
  • KPC
  • MDR
  • multi-drug resistance
  • NDM
  • NewDelhi metallo-B-lactamase