Human Papillomavirus (HPV), High Risk by Hybrid Capture, ThinPrep (INACTIVE as of 08/21/17: Refer to 2007893, 2011947)
Ordering Recommendation

FDA-approved test for routine cervical cancer screening in combination with cervical cytology (Pap smear) in women ≥30 years. Follow-up test for abnormal cytology results in women ≥21 years.
Other ThinPrep testing options include Human Papillomavirus (HPV), High Risk by Transcription-Mediated Amplification (TMA), ThinPrep (2007893), Human Papillomavirus (HPV), High Risk by PCR, ThinPrep (2011947), and Human Papillomavirus (HPV), High Risk with 16 and 18 Genotype by PCR, ThinPrep (2011940).

Qualitative Nucleic Acid Probe
3-10 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Females should avoid high concentrations of antifungal cream, contraceptive jelly, or douche at time of collection. 
Cervical Brush in ThinPrep transport media. 
Specimen Preparation
Place each specimen in an individually sealed bag. (Min: 4 mL) 
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated. 
Unacceptable Conditions
Specimens in any transport media other than indicated above. For specimens in SurePath transport media, refer to Human Papillomavirus (HPV), High Risk by PCR, SurePath (ARUP test code 2011942). For cervical brush specimens in Digene transport media, refer to Human Papillomavirus (HPV), High Risk by Hybrid Capture, Cervical Brush (ARUP test code 0065999). For ThinPrep specimens of less than 4 mL, refer to Human Papillomavirus (HPV), High Risk by Transcription-Mediated Amplification (TMA), ThinPrep (ARUP test code 2007893). 
Specimen source required. 
Ambient: 3 months; Refrigerated: 3 months; Frozen: Unacceptable 
Reference Interval
Interpretive Data
This test detects high-risk HPV genotypes 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68 associated with cervical cancer and its precursor lesions. However, cross-reactions with other genotypes may occur. Results should be correlated with cytologic and histologic findings. Sensitivity may be affected by specimen cellularity.

This test is intended for medical purposes only and is not valid for the evaluation of suspected sexual abuse or for other forensic purposes.

HPV testing should not be used for screening or management of atypical squamous cells of undetermined significance (ASCUS) in women under age 21.

For information regarding the comparison of HPV TMA and HPV Hybrid Capture assays, refer to this educational video: <>.
Component Test Code*Component Chart NameLOINC
0060752HPV Source31208-2
2008405HPV High Risk, Hybrid Capture, ThinPrep30167-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • HPV HR ThinPrep
  • HPV RNA, High Risk, E6/E7, TMA (Human Papillomavirus (HPV) DNA Probe, High Risk (ThinPrep)