Myeloproliferative Neoplasms Reflex Panel
2007418
Ordering Recommendation
Preferred panel in the workup of suspected myeloproliferative neoplasms.
Submit With Order
Mnemonic
MPD RFLX
Methodology
Polymerase Chain Reaction/Pyrosequencing
Performed
Varies
Reported
2-14 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA) OR bone marrow (EDTA).  
Specimen Preparation
Do not freeze. Transport 5 mL whole blood. (Min: 1 mL) OR 3 mL bone marrow. (Min: 1 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Serum. Specimens collected in anticoagulants other than EDTA. Clotted or grossly hemolyzed specimens.  
Remarks
 
Stability
Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable  
Reference Interval
Interpretive Data
Refer to report

See Compliance Statement B: www.aruplab.com/CS
Note
If JAK2 V617F is reported as "Not Detected," then JAK2 Exon 12 Mutation Analysis by PCR will be added. Additional charges apply. If JAK2 Exon 12 is reported as "Not Detected," then MPL codon 515 Mutation Detection by Pyrosequencing will be added. Additional charges apply.
CPT Code(s)
81270, if reflexed add 81403, if further reflexed add 81402
Components
Component Test Code*Component Chart Name
0051245JAK2 Gene, V617F Mutation, Qualitative
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • JAK2
  • MPL codon 515
  • MPN reflex
  • V617F