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Periodic Fever Syndromes Panel, Sequencing (7 Genes) and Deletion/Duplication, (6 Genes)
2007370
Ordering Recommendation

Most comprehensive test to identify causative periodic fever syndromes mutations.

Mnemonic
PRFEVERPAN
Methodology
Massively Parallel Sequencing/Exonic Oligonucleotide-based CGH Microarray
Performed
Varies
Reported
10-12 weeks
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA) or yellow (ACD Solution A or B). 
Specimen Preparation
Transport 3 mL whole blood. (Min: 1 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
 
Remarks
Submit the Patient History Form for Periodic Fever Syndromes with the Electronic Packing List. 
Stability
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable 
Reference Interval
By report
Interpretive Data
Refer to report.

Compliance Statement C: For human genetic inheritable conditions and mutations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Counseling and informed consent are recommended for genetic testing. Consent forms are available online.

Note
Hotline History
N/A
Components
Component Test Code*Component Chart NameLOINC
2007371Periodic Fever Panel Specimen31208-2
2007374Periodic Fever Panel Interp35474-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • chronic infantile neurological cutaneous and articular syndrome (CINCA)
  • neonatal onset multisystem inflammatory disease (NOMID)
  • Cyclic Neutropenia
  • ELANE/ELA2, LPIN2, MEFV, MVK, NLRP3/CIAS1, PSTPIP1, TNFRSF1A
  • Familial Cold Autoinflammatory Syndrome (FCAS)
  • Familial Mediterranean Fever (FMF)
  • Familial Mediterranean Fever (MEFV) Sequencing
  • Hyperimmunoglobulinemia D syndrome (HIDS)
  • Majeed Syndrome
  • Muckle-Wells Syndrome
  • Pyogenic Sterile Arthritis, Pyoderma Gangrenosum, Acne, (PAPA)
  • Tumor necrosis factor receptor-associated periodic syndrome (TRAPS)