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IGH-CCND1 Fusion, t(11;14) by FISH
2007226
Ordering Recommendation

Aid in diagnosis of mantle cell lymphoma if cyclin testing is noninformative.

Mnemonic
IGHCC FISH
Methodology
Fluorescence in situ Hybridization
Performed
Monday-Friday
Reported
3-7 days
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Tumor tissue. 
Specimen Preparation
Formalin fix (10 percent neutral buffered formalin) and paraffin-embed specimen. Protect paraffin block from excessive heat. Transport tissue block or 5 unstained (3-micron thick sections) positively charged slides in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787 (kit is recommended but not necessary). (Min: 2 slides) 
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months. 
Unacceptable Conditions
Specimens fixed or processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or B-5). No tumor in tissue. Decalcified specimens. 
Remarks
Include surgical pathology report. 
Stability
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable. 
Reference Interval
By report
Interpretive Data
Refer to report.

Compliance Statement A: For laboratory developed tests using a manufacturer labeled ASR as the reagent providing the specificity of the assay. Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.

Note
Hotline History
N/A
Components
Component Test Code*Component Chart NameLOINC
0049381IGH-CCND1 by FISH
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • IGH-CCND1 Fusion FISH
  • IGH-CCND1 Rearrangement FISH
  • t(11;14) FISH