Thyroglobulin by LC-MS/MS, Serum or Plasma
Ordering Recommendation

Recommended test for quantifying thyroglobulin in individuals with antithyroglobulin antibodies. Aids in surveillance of residual/recurrent thyroid cancer in individuals who have developed antibodies to thyroglobulin.

High Performance Liquid Chromatography-Tandem Mass Spectrometry
Mon, Wed, Thu, Sat
1-6 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum separator tube or green (sodium or lithium heparin), Potassium EDTA 
Specimen Preparation
Separate from cells: Transport 1.5 mL serum or plasma. (Min: 0.7 mL) 
Storage/Transport Temperature
Refrigerated or Frozen. 
Unacceptable Conditions
Samples left ambient for greater than 1 day 
After separation from cells: Ambient: 1 day; Refrigerated: 1 week; Frozen: 1 year 
Reference Interval
Reference Interval
6 months - 3 years7.4 - 48.7 ng/mL
4 - 7 years4.1 - 40.5 ng/mL
8 - 17 years0.8 - 29.4 ng/mL
18 years and older1.3 - 31.8 ng/mL

Interpretive Data
Lower limit of detection for Thyroglobulin by LC-MS/MS is 0.5 ng/mL.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Component Test Code*Component Chart NameLOINC
2007078Thyroglobulin by LC-MS/MS, Serum/Plasma3013-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.