BRAF V600E Mutation Detection by Allele-Specific PCR, Fine Needle Aspirate
2006516
Ordering Recommendation
Molecular test for the detection of the BRAF V600E mutation in direct smear specimens from fine needle aspirate (FNA). For tissue block or formalin-fixed, paraffin-embedded cell blocks prepared from FNA, may use BRAF codon 600 Mutation Detection by Pyrosequencing (2002498).
Mnemonic
BRAF FNA
Methodology
Polymerase Chain Reaction
Performed
Varies
Reported
7-10 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Tumor cells by Fine Needle Aspiration (FNA).  
Specimen Preparation
Prepare FNA smear and Diff-Quick or equivalent stain by standard methods.  
Storage/Transport Temperature
Two FNA slides (min: 1 slide) Transport slide(s) in a tissue transport kit (ARUP supply # 47808) available online through eSupply using ARUP Connect™or contact ARUP Client Services at (800) 522-2787.  
Unacceptable Conditions
Slides with less than 50 atypical or tumor cells.  
Remarks
Include cytology report. For a general FNA collection and smear preparation refer to ARUP's Laboratory Test Directory: Cytology, Fine Needle Aspiration Collection at http://www.aruplab.com/guides/ug/tests/arup014.jsp  
Stability
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable  
Reference Interval
   
Interpretive Data
Refer to report.

See Compliance Statement B: www.aruplab.com/CS
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
 
CPT Code(s)
88381; 81210
Components
Component Test Code*Component Chart Name
2006517BRAF V600E Mutation Detection, FNA
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • BRAF V600E mutation FNA
  • Thyroid FNA BRAF