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Zinc Transporter 8 Antibody
2006196
Ordering Recommendation

Most useful to establish autoimmumne etiology in previously diagnosed type 1 diabetes mellitus (DM). Do not use to differentiate type 1 DM from type 2 DM, for most cases.
If pursuing antibody testing to determine autoimmune DM, perform at least two antibody tests. In most cases, use glutamic acid decarboxylase antibody in combination with another antibody test. Other antibody tests include Glutamic Acid Decarboxylase Antibody (2001771), Insulin Antibody (0099228), and Islet Cell Cytoplasmic Antibody, IgG (0050138).

Mnemonic
ZNT8 AB
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Wed
Reported
1-8 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube or plain red. 
Specimen Preparation
Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Plasma. Grossly hemolyzed or severely lipemic specimens. 
Remarks
 
Stability
After separation from cells: Ambient: 5 days; Refrigerated: 1 week; Frozen: 3 months 
Reference Interval
0.0-15.0 Kronus Units/mL
Interpretive Data
A value greater than 15.0 Kronus Units/mL is considered positive for Zinc Transporter 8 antibody( ZnT8 ).
Kronus Units are arbitrary. Kronus Units = U/mL. This assay is intended for the semi-quantitative determination of antibodies to ZnT8 in human serum. Results should be interpreted within the context of clinical symptoms.

Note
Hotline History
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Components
Component Test Code*Component Chart NameLOINC
2006197Zinc Transporter 8 Antibody76651-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • ZnT8
  • ZnT8 antibodies
  • ZnT8A