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Methylmalonic Acid, Serum or Plasma (Metabolic Disorders)
2005255
Ordering Recommendation

This test is used to evaluate and monitor methylmalonic acidemia.

Mnemonic
MMA METD
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Plain red or serum separator tube. Also acceptable: Green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA). 
Specimen Preparation
Centrifuge and remove serum or plasma from cells within 2 hours of collection. Immediately transfer 2 mL serum or plasma to an ARUP Standard Transport Tube and
refrigerate or freeze. (Min: 1 mL) 
Storage/Transport Temperature
Frozen. 
Unacceptable Conditions
Room temperature specimens. Grossly hemolyzed or lipemic specimens. 
Remarks
 
Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month 
Reference Interval
Effective July 18, 2011

0.00-0.40 µmol/L
Interpretive Data


Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Components
Component Test Code*Component Chart NameLOINC
2005256MMA Serum/Plasma, Metabolic Disorder13964-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • MMA (Methylmalonic Acid, Serum or Plasma (Metabolic Disorders))