Cytokeratin 5,6 (CK 5,6) by Immunohistochemistry
Ordering Recommendation
1-3 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Immunohistochemistry Stain Form Recommended  (ARUP form #32978)Immunohistochemistry Stain Form Recommended (ARUP form #32978)

Specimen Required
Patient Preparation
Tissue or cells.  
Specimen Preparation
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Protect paraffin block and/or slides from excessive heat. Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides in a tissue transport kit (ARUP supply #47808). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 2 slides). If sending precut slides, do not oven bake.  
Storage/Transport Temperature
Room temperature or refrigerated. Ship in cooled container during summer months.  
Unacceptable Conditions
Specimens submitted with non-representative tissue type. Depleted specimens.  
IMMUNOHISTOCHEMISTRY ORDERING AND SUBMISSION DETAILS: Submit electronic request. If you do not have electronic ordering capability, use an ARUP Immunohistochemistry Stain Form (#32978) with an ARUP client number. For additional technical details, contact ARUP Client Services at (800) 522-2787.  
Ambient: Indefinitely, Refrigerated: Indefinitely, Frozen: Unacceptable  
Reference Interval
Interpretive Data

See Compliance Statement B:  
All stains will be handled as "Stain and Return" unless a consultation is requested. To request a consultation, submit the pathology report, all associated case materials (clinical history, blocks, slides, etc.), and the Anatomic Pathology requisition form (form # 32960) in place of the Immunohistochemistry Stain Form.
CPT Code(s)
Component Test Code*Component Chart Name
2003852Cytokeratin 5,6 by IHC
2003853Cytokeratin 5,6 Reference Number
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • CK 5,6
  • CK 5,6 staining
  • CK5,6 IHC
  • cytokeratin 5,6 IHC
  • Cytokeratin 5,6 staining