Quetiapine, Serum or Plasma
Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Quantitative Liquid Chromatography-Tandem Mass Spectrometry
1-8 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2 EDTA). 
Specimen Preparation
Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution). 
Ambient: 1 week; Refrigerated: 1 month; Frozen: 1 month 
Reference Interval
Interpretive Data
The following therapeutic ranges and toxic values have been suggested but have not been validated.
Adverse effects may include somnolence, dizziness, fatigue, constipation, weight gain.

Predose Draw (Trough) - Preferred
Therapeutic range70-170 ng/mL
Toxic:Greater than 1000 ng/mL

Peak Draw (1.5 hour post dose) - Not recommended
Therapeutic range100-1000 ng/mL
Toxic:Greater than 1500 ng/mL

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Hotline History
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CPT Code(s)
Component Test Code*Component Chart NameLOINC
2003119Quetiapine, Serum/Plasma26776-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
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